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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Morphological parameters rat testes in normal conditions, with the background of chronic radiating disease and under the influence of an antiseptic stimulator

Author: TESHAEV J, BAYMURADOV R R, KHAMIDOVA N K, KHASANOVA D A
Abstract: The goal is to study the morphological parameters of the testes of rats of three (03) months of age, normal, with the background of chronic radiation sickness and when exposed to an antiseptic stimulator. Materials and methods. The study was conducted on sixty (60) white randomly bred male rats, weighing from 91 to 116 g, divided into three (03) groups. Chronic radiation sickness was caused by irradiation of rats (4 Gy), ASD-2 was chosen as an antiseptic stimulator. Animals were removed from the experiment at ninety (90) days of age, and twenty (20) days after its inception. Mathematical processing was also performed in which the standard deviation and representativeness errors were determined. Results. An analysis of the results showed that in rats of the first experimental group with chronic radiation sickness at puberty, the diameter of convoluted seminiferous tubules is 8% less than the control, and their cross-sectional area is 13% behind. But in rats of the 2-experimental group that received ASD-2 at ninety (90) days of age, the diameter of the convoluted seminiferous tubules increases by 4% compared with the 1-experimental group, and their cross-sectional area is 6% larger. Conclusions. It was established that after exposure to chronic irradiation, puberty is delayed and all morphological parameters of the testes lag behind. But when using an antiseptic stimulator, the pathological effect of radiation sickness on the structural elements of the testes decreases, which affects the morphometric parameters.
Keyword: Testes, convoluted tubules, morphological parameters, chronic radiation sickness, an antiseptic stimulator
DOI: https://doi.org/10.31838/ijpr/2021.13.01.676
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