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Content of Phagocytic Activity of Monocytes and Neutrophils in Twin Children with Inflammatory Diseases of the Paranasal Sinuses
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| Author:
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, UBAYDULLO I NUROV, SAYFIDDIN S ARIFOV
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| Abstract:
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The aim of the carried research was to study the functional activity of monocytes and neutrophils in sick twin
children with IDPS (inflammatory diseases of the paranasal sinuses) in a comparative aspect with non-twins. It
was noticed that with various rhinosinusitis in children PhAM level (phagocytic activity of monocytes) in the
blood decreases which causes the development of a chronic purulent focus and forms conditions for
intracellular persistence of viruses is characterized by an increase in monocytes with viral inclusions. When
incubating the blood of patients with IDPS (inflammatory diseases of the paranasal sinuses) and healthy children
with antibiotics in vitro, significant suppression of PhAM was revealed. This is particularly pronounced when
blood is incubated in vitro in sick children with ceftriaxone and Ciprox. In patients with IDPS the activity of
non-specific protective factors of the body is significantly reduced, which is expressed in a decrease in PAM
indicators along with the increase in monocytes with viral inclusions in vitro, in fact, which is more
pronounced in twin children than in non-twin children.
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| Keyword:
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IDPS (Inflammatory diseases of the paranasal sinuses), FAM and PhAM (functional and phagocytic activity of monocytes), twin children, NBT (nitroblue tetrazolium) test
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.677
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| Download:
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