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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Epithelioid Malignant Peripheral Nerve Sheath Tumor of Sciatic Nerve: a Case Presentation and Literature Review

Author: REZA TAVAKOLI DARESTANI, FARZAD AMOUZADEH OMRANI, MOHAMADMAHDI OMIDIAN, HAMED HAKIMI ASIABAR, MOHAMMAD AMIN SHAHRBAF, HASSAN BARATI
Abstract: Background: Malignant peripheral nerve sheath tumors (MPNSTs) are a bunch of soft tissue tumors that can involve nerves or their sheaths. The symptoms of these lesions can be confused with other disease like discopathy. One of the subtype of these tumors is epithelioid sarcoma. In this study, we report a rare case of epithelioid sarcoma of sciatic nerve that present with first diagnosis of discopathy. Case Presentation: We presented a 44-year-old man with pain of buttocks, paresthesia and paraplegia that was treated conservatively as a lumbosacral discopathy but his symptoms didn’t reveal. MRI showed us a sciatic involvement. The patients underwent an operation for excisional biopsy and the diagnosis of epithelioid sarcoma was made for patient. There wasn’t any evidence of metastasis in follow up. We planned a wide resection surgery after radiotherapy for treatment of patient. Conclusion: Epithelioid sarcoma of sciatic nerve is extensively rare that can be miss diagnosed with lumbosacral discopathy. We have to consider this diagnosis in patients with recurrent period of discopathy.
Keyword: Sarcoma, Sciatic Nerve, Neurofibrosarcoma, Neoplasm.
DOI: https://doi.org/10.31838/ijpr/2021.13.01.679
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