IJPR  articles are Indexed in SCOPUS (2010 - 2021)Click Here     *Five Years Citation in Google scholar (2016 - 2020) is. 1451*        Now IJPR is Q2 in SJR Ranking     Scopus Coverage of IJPR (2010-2021 Issue 1)            

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Analytical and Bio-Analytical Method Development and Validation of Chlorpyrifos Pesticide by RP-HPLC Method

Author: ANDREWS KT, CHANDAN R S
Abstract: Organophosphate pesticides are widely used throughout the globe and in developing countries, contamination by these blends is a veritable general wellbeing safety concern. Chlorpyrifos is a wide range pesticide utilized broadly, since 1965 for horticultural and household pest control. CP's belongs to secondary pesticides which possess moderate toxicity as per WHO classification. For the estimation of Chlorpyrifos, an ultra-fast liquid chromatography (RP-HPLC) method was processed, which is fast, sensitive, versatile and economical. Work on the Shimpack GIST C18 (250 x 4.6 mm. 5 µ) was accomplished with the M.P ratio of MeOH and acetonitrile (50:50 v/v) at 1.0mL / min. With a framework of UV detection, at 290 nm, the Eluent was tracked. CP’s elutes at a time of persistence of 3.926 min. The coefficient of correlation was found to be 0.9907 for analytical and 0.9982 for bio-analytical method, over a linear spectrum of 1-5 µg/ml. LOD and LOQ are estimated at 0.045 and 0.137µg/ml for the proposed procedure. In compliance with ICH standards both Analytical and Bio-Analytical methods was tested.
Keyword: UV detector, RP-HPLC, Chlorpyrifos, organophosphate, ICH guidelines
DOI: https://doi.org/10.31838/ijpr/2021.13.02.002
Download: Request For Article
 




ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free