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Chili Peppers Extract Could Prevent Kidney Stone
Incidence
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| Author:
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ANAS KHALEEL, TALAL SALEM AL-QAISI, ABDALLAH AHMED ELBAKKOUSH, MOHAMMAD NIAZI, HUSNI S FARAH, KHALED ABDUL-AZIZ AHMED, RAFAT ABUTALEB
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| Abstract:
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Background: Capsaicin, cayenne, or chili pepper is all belonging to the plants of the Capsicum genus. The primary and most-studied active ingredient in the plant is capsaicin and was approved by the U.S. Administration of Food and Drugs (FDA). More research is needed on other capsaicin uses to find out if it is helpful for the treatment or prevention of kidney stones.
Methods: Literature shows there could be health benefits associated with ingestion of chili pepper extract. We developed a recommendation based on several promising results, highlighting the possible relation between chili pepper extract and kidney stone reduction.
We searched the literature for beneficial effects of chili pepper on kidney stones and identified the relationships that could lead to the prevention of kidney stones.
Results: Depending on several observations such as TRPV1 protein activation by pepper extract ingestion. We have shown that the activation of TRPV1 by ingestion of pepper extract may be protective against kidney stone development. Several relationships that may lead to kidney stone prevention were established to prove the prevention theory.
Conclusions: Here, we propose that kidney stones are prevented by continuous dietary capsaicin intake. According to our results, capsaicin consuming individuals with a history of kidney stone may have significantly low susceptibility to kidney stone incidence. In support of the many validated health benefits, frequent ingestion of red chili pepper was associated with reduced risk of kidney stone. Further studies may be needed to confirm the efficacy and assess the safety of capsaicin.
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| Keyword:
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kidney stone; Capsaicin; Capsicum; red pepper; TRPV1
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.628
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| Download:
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