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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Role Of Dental Pulp Stem Cells In Restoring Vision- Narrative Review

Author: NEETHU ANN PREETHY.P, AHSANA.A, DR.DEEPA GURUNATHAN, DR.LAKSHMI.T
Abstract: Stem cells are clonic cells capable of self renewal and multi lineage differentiation. Stem cells of dental origin include Dental pulp stem cells(DPSC), Stem cells from Human Exfoliated Deciduous Teeth(SHED), Periodontal Ligament Stem Cells(PDLSC), and Stem Cells from Apical Papilla(SCAP). DPSC and SHED are unspecialised neural crest derived ectomesenchymal cells isolated from dental pulp of extracted teeth and exfoliating primary teeth. The mode of action by which SHED and DPSC provides therapeutic benefit includes multiple pathways namely paracrine mediated process which involve a range of secreted trophic factors . It provides neuroprotection and regeneration of retinal ganglion cells and aids in the repair and treatment of optic nerve injury and glaucoma thereby restoring vision
Keyword: Stem cells, Dental, retina, optic nerve, vision
DOI: https://doi.org/10.31838/ijpr/2020.12.04.633
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