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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Chalcone-Heterocyclic Derivatives (Synthesis, Spectral Identification, Microbial Evaluation)

Author: HUTHAM ABD ALI ABD AL HUSSAIN, DR.NAGHAM MAHMOOD ALJAMALI
Abstract: A circular compound is a chemical compound that consists of a series of atoms that are periodically bound together. The majority of cyclic compounds are organic compounds, but there is a small percentage of inorganic cyclic compounds, including: sulfur, silicon, which forms silicon, and phosphorous, which forms phosphorous compounds. Some types of heterocyclic compounds are aromatic, such as pyridine. The concept of a polycyclic compound is used when one molecule consists of more than one ring, such as a compound naphthalene, and the concept of a massive cyclic compound is used when it contains more than ten atoms. The object in this study is preparation of chalcone-heterocyclic compounds (Five, Six, Seven)-membered ring by cyclization step via reaction with amine derivatives like (semicarbazide, thisemicarbazide, hydrazine, thio amide derivative,….). All new synthesized compounds identified through types of instrumental methods like (FT.IR, H.NMR, Mass)–spectrophotometric, other chemical investigations, with evaluation of prepared compounds as antimicrobial compounds.
Keyword: Chalcone, Seven Membered, Six Membered, Five Membered Ring, Antimicrobial, Heterocyclic.
DOI: https://doi.org/10.31838/ijpr/2021.13.01.634
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