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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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COVID-19 Triggers The Incidence of Diabetic Ketoacidosis: A Case Report of Uncontrolled Type 2 Diabetes Mellitus

Author: SULTAN M. ALSHAHRANI, NAJIM Z. ALSHAHRANI , KHALED M. ALAKHALI
Abstract: Background: The new COVID-19 has been reported as a risk factor for diabetic ketoacidosis in patient with diabetes mellitus type 1 or 2. Diabetes mellitus is associated with several micro- and macro- vascular complications. Diabetic ketoacidosis is occurred as a result of imbalance between insulin and its counterregulatory hormones. Case Report: A 33-year-old male has presented to emergency department with polyuria, polydipsia, and lethargy for three days. He was tested positive with SARS-COV-2. The patient showed morbid obesity and he was on several self-medication products and home remedies for treating COVID-19. Laboratory confirmed the hyperglycemia where random blood glucose level was between 255-345 mg/dl and A1C was 11.66%. Ketone bodies were detected in the urine. Poor diabetes control, infection, obesity, and persistence hyperglycemia have also precipitated the occurrence of diabetic ketoacidosis. The patient was resuscitated with fluids and insulin therapy. After 24 hours, the diabetic ketoacidosis symptoms were resolved. Conclusion: Patients with diabetes mellitus should be aware of the importance of medication adherence and diet control. Further studies on the relationship between the infection with SARS-COV-2 and the incidence of diabetic ketoacidosis will delineate the pathophysiological mechanism.
Keyword: Diabetic ketoacidosis, Obesity, COVID-19, T2DM
DOI: https://doi.org/10.31838/ijpr/2021.13.01.519
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