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Association of additive risk of INC I gene with the presence of Diabetes Type 1 and Type 2
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| Author:
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AWS RASSUL HUSSAIN AL-SALIH
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| Abstract:
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The aim of the present research was to define the protective role. In which insulin that is required for survival is not developed by the pancreas. But is increasingly found later in life. Type 2 diabetes results from the body's inability to respond properly to the action of insulin released by the pancreas. Instructions for the hormone insulin synthesis are given by the INS gene, which is necessary for the hormone insulin. The aim of the work: Gene comparison between a healthy person and a person with diabetes type 1 and type 2.Materials and method: this study was conducted from 2017 to 2019, 80 patients with diabetes mellitus after being medically diagnosed and the presence of INS I polymorphisms associated with high risk of diabetes mellitus. DNA was extracted and molecular detection was performed to detect single nucleotide polymorphisms (SNPs) at genetic sites using PCR and PCR-RFLP techniques. The results: The diagnosis of a genetic INS I in healthy people, unlike in patients with diabetes, was not found and the level were low in type 1 diabetus.
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| Keyword:
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diabetes mellitus, INS I gene, PCR-RFLP.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.574
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| Download:
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