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Article Detail
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Development of A Vaccine Against Infectious Rhinotracheitis, Parainfluenza-3, Viral Diarrhoea And Chlamydia in Bovine Cattle
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| Author:
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VITALY V. EVSTIFEEV, VALI G. GUMEROV, ILGIZAR R. AKBASHEV, GULNARA I. KHUSAINOVA, ILSYAR G. KARIMULLINA, AINUR I. YARULLIN, SVETLANA V. IVANOVA, RUSTAM KH. RAVILOV, ALBERT K. GALIULLIN, DANIL N. MINGALEEV, ANATOLY I. TRUBKIN, OKSANA V. KOCHETOVA
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| Abstract:
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It should be noted that when monovaccines are used in farms, it is difficult to draw up an inoculation calendar, as it is necessary to observe a certain interval when forming full immunity between individual vaccinations. The use of associated vaccines could significantly reduce vaccination costs, reduce sheep productivity losses due to stress and animal injuries during vaccination. The use of associated vaccines as well as comprehensive and associated immunisation, as compared to multiple vaccinations with different monovaccines, has now been shown to have clear advantages in terms of significantly reducing the time required to establish immunity to multiple infections at the same time, improving cumbersome preventive vaccination schemes and reducing reactive reactions. The main advantages of associated vaccines, comprehensive and associated immunization are that the number of injections is sharply reduced and the number of antigens injected does not decrease. Etiological structure of pathogens was established on the basis of clinical-epizootic and laboratory studies. At the present stage, the role of viral diarrhoea - mucous membrane disease (VD-MD), together with viruses of parainfluenza-3 (PF-3), infectious rhinotracheitis (RTC) and chlamydia in the etiology of respiratory and intestinal diseases in bovine cattle was proved. The dynamics of specific antibodies formation after single and double vaccination was studied; immunogenic activity of associated vaccine against RTC, PF-3, VD-MD and cattle chlamydia in laboratory conditions was established. Based on the results of production trials, the effectiveness of the developed associated vaccine for the prevention of morbidity in conditions of pneumoenteritis and diseases of reproductive organs in livestock farms was proven. A cost efficiency calculation was also carried out.
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| Keyword:
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associated vaccine, viral diarrhoea, parainfluenza-3, infectious rhinotracheitis, chlamydia, vaccination, cattle, abortion, diarrhoea, respiratory diseases.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.492
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| Download:
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