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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Vaccination prior to initiation of anti-TNF therapy

Author: NADA ALSALEH
Abstract: Anti-TNF therapy is widely used for the treatment of inflammatory diseases. This immunosuppressive therapy comes with a few complications that could be life-threatening. TNF prepares the immune system of the body for any foreign infections. When this factor is inhibited, immune system can be easily compromised and risk of influenza, pneumonia, herpes zoster, hepatitis B, and meningitis is considerably increased. This complication needs to be addressed critically before starting anti-TNF therapy. Vaccination prior to immunosuppressive therapy is found to be effective in reducing such complications. Rates of vaccination can be optimized by enhancing patient compliance, removing financial barriers, and educating both patients and their families. Patient personalized appeal letter for vaccination was also found to be an effective intervention. Educating and updating the healthcare providers with the latest technologies and software can help in proper documentation and scheduling vaccine administration properly.
Keyword: anti-TNF therapy; infections; vaccination; immunization
DOI: https://doi.org/10.31838/ijpr/2021.13.01.439
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