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Development and evaluation of bio nanocomposite films for antifungal activity
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| Author:
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PRASAD VINAY RAO, MEENAKSHI S, AFRASIM MOIN, NANHI NANDINI, AMIT B PATIL, SIDDARAMAIAH, NITHIN K S, D V GOWDA
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| Abstract:
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Aim: The aim of the present study was to develop Bio Nano composite films (BNCFs) by green process for antifungal activity.
Methods: Silver nanoparticles (AgNPs) coated with Badam gum (BG) and clove extract (CE) by green process and fabricated into poly- lactic acid (PLA) based antifungal Bio Nano composite films (BNCFs) by solvent casting method.
Results: Green synthesis was used to coat the silver nanoparticles with badam-gum and clove extract fabricated into Bio-Nano composite films by using poly- lactic acid. Peak observed at 340nm by UV-visible spectroscopy indicates the presence of silver nanoparticles. X-Ray Diffraction was used to study the crystallinity of nanoparticles and Scanning Electron Microscope/ Energy Dispersive X-Ray Spectroscopy analysis was performed to support the presence of silver nanoparticles on badam gum. The films were prepared and impregnated with badam gum as 7% and 10% in which 10% showed wider zone of inhibition of 16mm diameter resulting better inhibitory effect against Candida albicans exhibiting anti-fungal activity of badam gum with silver nanoparticles/Poly lactic acid bio nanocomposite films. In conclusion, prepared bio nanocomposite films exhibit significant antifungal properties.
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| Keyword:
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Bio Nano composite films, silver nanoparticles, Candida albicans, anti-fungal activity, badam gum, poly lactic acid.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.446
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| Download:
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