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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Pharmacological studies of Celastrus paniculatus -A Review

Author: SHALU ATTAR, RAHUL KUMAR SHARMA
Abstract: In the whole world India is one such country which have great diversity of natural plants, which are proven to be have medicinal significance from ancient time. These medicinal plants are being used in modern medicine for the treatment of different human ailments. A significant proportion of the commercial medication is focused on bioactive factors obtained from the plants. Celastrus paniculatus is one of the major medicinal plants which being used to treat many human ailments. Celastrus paniculatus is commonly developed as a staff tree and a black oil plant belonging to the Celastraceae family, found abundantly in India at 1250 meters above sea level, and also widely grown in Indonesia, Laos, Maharashtra, Orissa and Andaman Nicobar group of Islands. This plant is full of various bioactive metabolites like simple sugars, proteins, amino acids and lipids and alkaloids (celastine, celapanine, celapanigine, celapagine,) glycosides, tannins, fatty acids (Oleic, Linoleic, Linolenic, Palmitic, Stearic, Crude Lignoceric acid), phenolic compounds, protein, flavonoids, saponins and sesquiterpens etc. which are responsible for various pharmacological activities of this plant. Celastrus paniculatus is used for the treatment of various ailments from the ancient time that is why named as “ Elixir of life” in Ayurvedic system of medicine traditionally it is used as a nerve tonic, sedative, tranquilizer, aphrodisiacs, laxative, appetizer, emetic, snakebite, dysentery, colds, gout, hemorrhoids, leprosy etc. Scientifically this plant is reported for various pharmacological activities like antioxidant, hypolipidemic, neuroprotective, nootropic, cytotoxic, antidepressant, antifertility, antibacterial, antifungal, antimalarial etc.
Keyword: Celastrus paniculatus, bioactive metabolites, Ayurvedic system
DOI: https://doi.org/10.31838/ijpr/2021.13.01.387
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