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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Review on Ionic Liquids: Green Solvent for Extraction of Herbal Active Ingredients from Medicinal and Aromatic Plants

Author: SANDEEP B. MUNDHE, SUYOGKUMAR V. TARALKAR, PRAKASH G. JADHAV, SANJAY B. DETHE
Abstract: Extraction is a commonly used mass transfer operation in many chemical and pharmaceutical industries and it has been a favored choice in separation processes. This review article focuses on ionic liquid assisted extraction methods in the isolation of active ingredients. Ionic liquids (ILs) at room temperature are a set of liquid that exhibit variety of possible anion and cation combinations giving required property combinations. The desirable and adjusting properties of ionic liquid make it a designer solvent. The term Active Ingredients (AI) represents the ingredients act as rich active bio-source in the drugs used in traditional, modern medicine system, pharmaceuticals, nutraceuticals, food supplements, folk medicine and extracted from medicinal and aromatic plants MAP. This review presents the application of ILs as a solvent, co-solvent or supported material in the extraction of medicinally active ingredients from MAPs, listing flavonoids, alkaloids, carbohydrates, anthraquinones, amino acids, enzymes, vitamins, minerals, polysaccharides etc. Many studies have reported for effective extraction of such active ingredients using traditional volatile solvents, but use of ionic liquid as solvent make efficient performance difference in liquid –liquid, solid-liquid and ionic liquids –modified material extraction. This article reviews and compare performance of extraction of such critical active ingredients.
Keyword: Active ingredients, Ionic liquid, Medicinal and aromatic plants.
DOI: https://doi.org/10.31838/ijpr/2021.13.01.335
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