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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Characterisation Of Encapsulated Beta Vulgaris Linn.Dry Powder Extract In Chitosan

Author: SANGGITA AYU IKASARI, ANITA SUKMAWATI
Abstract: Beet (Beta vulgaris Linn.) (BV) root is one of the natural ingredients that has antioxidant agent because of the content of phenolic compounds.. However, the challenge in formulating beet root extract into cosmetics preparations is its stability. Therefore, the microencapsulation was chosen in order to maintained its stability. Chitosan was chosen as a matrix as it has a good release of drug in biological fluid. The microencapsulation of BV extract was carried out in various chitosan solution (0.5, 1 and 2%) using precipitation method using sodium tripolyphospahte (TPP). The evaluation of microparticle including size ditribution and the entrapment efficiency (EE). The results showed particle size distribution had positive skewed. The low concentration of chitosan (0.5%) produced the high frequency of particle in the range of 10-29 µm. Increasing the chitosan concentration to 1 and 2 % reduce the number of particle in the range 10-29 µm. The entrapment efficiency evaluation using indirect method showed that the BV root extract had a good entrapment in chitosan.
Keyword: Beta vulgaris Linn, chitosan, microencapsulation, entrapment efficiency
DOI: https://doi.org/10.31838/ijpr/2021.13.01.159
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