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Features of Diagnostics and Treatment of Drug-Resistant Forms of Pulmonary Tuberculosis
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| Author:
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, ISOMIDDIN KH. USMONOV, BAHODIR R. MUAZZAMOV, MUHTOR F. JUMAEV
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| Abstract:
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The study is based on the survey data of 152 patients with drug-resistant forms of tuberculosis who received inpatient treatment at the Bukhara Regional Center for Phthisiology and Pulmonology in the period 2016-2019. The age of the patients varied from 19 to 79 years, the average age was 62.8 years. In men, the disease occurred 2.04 times more, and 73.0% of patients were over the age of 50. In a comparative analysis, it was noted that more often the disease occurred in the rural population in 110 (72.4%) cases, while in urban patients this figure was 42 (27.6%). It should be noted that in 23 (15.1%) cases the patients were secondary, who had previously received treatment for sensitive forms of pulmonary tuberculosis. Infiltrative pulmonary tuberculosis was often encountered - in 143 (94.0%) patients, an advanced form of fibrous-cavernous tuberculosis - in 3 (2.0%) cases, and an early form of focal pulmonary TB was observed in 3 (2.0%) cases. A bacteriological study of sputum with molecular genetic (Gene Expert, HAIN Test) methods and methods of inoculation on liquid (MGite BACTEK 960) or solid (Lowenstein - Jensen) media was carried out, followed by the detection of the sensitivity of Mycobacterium tuberculosis to anti-tuberculosis drugs, and the use of these methods improved the results of treatment.
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| Keyword:
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drug-resistant pulmonary tuberculosis, diagnosis, treatment.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.406
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| Download:
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