|
Reappraisal of the Effect of Helicobacter pylori Eradication Treatment on Rosacea in Iraqi Patients
|
|
| Author:
|
SAMER A DHAHER
|
| Abstract:
|
Background: Rosacea is a chronic inflammatory skin disease where Helicobacter pylori being involved in its etiopathogenesis is still controversial.
Aim: To evaluate whether H. pylori eradication treatment will improve the clinical features of rosacea in Iraqi patients.
Patients and Methods: a prospective study includes 56 patients with papulopustular rosacea subtype underwent urea breath test and if the test was positive, they were treated for 2 weeks with H pylori eradication kit. Patients were evaluated at baseline, 30 and 60 days follow up periods using the standard grading system of rosacea plus the numerical count of the lesions.
Results: The mean age±SD was 46.7±5.1 years, 96.3% were female. Urea breath test was positive in 44(77.8%). After treatment with H pylori eradication therapy, the mean total score of the standard grading system of rosacea was significantly reduced from 12.4±4.02 at baseline to 7.7±2.71and 6.8±2.6 at day 30 and day 60 follow-ups respectively (p <.005). Lesions count was significantly reduced at day 60 compared to baseline (53±23 versus 5.1±6.4, p<0.005), 45(83%) patients were scored excellent, while only 2(3.7%) responded poorly.
Conclusion: our results support the link between H pylori and rosacea especially in the papulopustular subtype, and a substantial number of patients were improved after eradication of H pylori infection.
|
| Keyword:
|
Helicobacter, pylori, eradication, rosacea
|
| EOI:
|
-
|
| DOI:
|
https://doi.org/10.31838/ijpr/2021.13.01.376
|
| Download:
|
Request For Article
|
|
|