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Dissolution profile comparison of two marketed Favipiravir tablets
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| Author:
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SANDEEP KHATALE, CHAUDHARI NIKHIL SURESH, ANAGHA UPASANI, NILAM BHUSARE
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| Abstract:
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COVID-19 pandemic has devasted world since December 2019. Many countries being affected by the deadly virus has implemented lockdown to slowdown the spread of virus. As the disease condition is new to everyone many experimental drugs are being introduced. Hydroxychloroquine considered to be found to be not effective. Then drug which were originally used as antiviral agents such as disease treatment. Favipiravir is RNA dependent RNA polymerase inhibitor which commonly used in Avian flu to control disease spread found to be effective aid in the Novel COVID-19 disease conditions. In this study we have compared two marketed different tablets of FAvipiravir for their dissolution studies. Dissolution studies were done simultaneously to avoid errors. Tablets was found to be immediate release. The percent drug release for fabiflu is 113.84 and percent drug release for Fviflow is 127.91. The Fabiflu tablet has shown reliable dissolution profile compared to the Faviflow tablets and found to be within limits.
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| Keyword:
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Favipiravir, Dissolution, Hydrochloric acid, Percent drug Release, Fabiflu.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.368
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| Download:
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