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Can IL1ß and IL10 levels assessment in endometrial secretion predict pregnancy outcome after ICSI? A prospective study.
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| Author:
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TAIF EIMAD AHMED, FADIA J AL-IZZI, QAYS AHMED MAHDI
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| Abstract:
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There is a significant role of cytokines in implantation process. The aim of our study was to assess the concentrations of interleukin 1 beta (IL1ß) and interleukin 10 (IL10) in the endometrial secretions and their relation to success of intra-cytoplasmic sperm injection (ICSI). A prospective cohort study done at Kamal Al-Samarraei hospital for infertility management and in-vitro fertilization (IVF) for 37 patients undergoing controlled ovarian stimulation with gonadotropin- releasing hormone (GnRH) antagonist. A non-invasive way of endometrial lavage was performed immediately after oocyte retrieval (OR) to measure the concentration of both interleukins (ILs) by Enzyme-Linked Immunosorbent Assay (ELISA) technique. Our result was that both ILs were non- significantly higher in patients with a successful pregnancy. We concluded that early assessment of IL1ß and IL10 in endometrial secretion may predict pregnancy outcome
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| Keyword:
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Endometrial receptivity, Cytokines, IVF/ ICSI, Implantation.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.355
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| Download:
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Request For Article
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