Componential Description Of Medicated Foams: A Review
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Author:
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HAYDER HUSSEIN ALWAN, HANAN JALAL KASSAB
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Abstract:
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This paper aims at offering an overview of foams as new topical drug delivery vehicles that possess promising marketing potential and advantages as well as gaining positive patient compliance. The overview surveys medicated foams by defining their structure, and components (foaming agents, boosters, stabilizers, and reducers) that can be optimized upon actuation to enhance their skin penetration advantages and, consequently, their bioavailability. It also touches upon the main methods used in foam production (whipping, bubbling, and pressurization). Processes involved in determining foam stability - which is a vital property for its pharmaceutical application - are categorized. As a means of pharmaceutical delivery vehicle, the description covers dermal, otic, rectal, and vaginal foams. Specific delivery means include: dry foams, foam dressings, and DepoFoams. The paper is concluded by methods of evaluating foams macroscopically and microscopically. The implication of the study justifies encouraging further in-depth research work to explore medicated foams scope of potentiality.
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Keyword:
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drug delivery; patients; medicated foams;
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EOI:
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-
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DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.349
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