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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Type 2 Diabetes Mellitus and Its Effect on Quality of Life among Adolescent Population: A Retrospective Cohort Study in Saudi Arabia

Author: , SIREEN A. SHILBAYEH, WEDYAN A. ALHUSSAIN, ALANOUD S. ALHIBS, NAJLA G. ALMALKI, NOUF A. ALMAJHAD, SAMAR T. NOURI, SARAH M. ALSALEH
Abstract: Objectives: Quality of life (QoL) in adolescent patients suffering from type 2 diabetes mellitus (T2DM) has not been explored much in Saudi Arabia. Herein, this study aims at measuring the health-related quality of life (HRQoL) in adolescent patients suffering from T2DM and exploring the correlation between adolescents' self, parent-reports of QoL scores, and glycemic control (HbA1c). Methods: A retrospective multi center cohort study was conducted at four hospitals in Riyadh, Saudi Arabia. The Pediatric Quality of Life Inventory (PedsQLTM) Diabetes Module 3.0 was completed by children and their parents in a confidential and anonyms approach through a phone interview. Results: We recruited 49 pediatric patients for this study (mean age: 18.45; male: 55%). Both children and parents reported low cumulative mean scores for PedsQL™ (58.65 and 57.38, respectively) as compared to previous international studies. The lowest obtained score was noted for the diabetes symptoms domain (53.4). Comparing the magnitude of discrepancy between the adolescent and parents' subscales' scores revealed non-significant difference, except for the ‘worry’ subscale, where parents reported significantly higher mean scores (76.73 vs. 60.54, P= 0.02). Comparison of mean scores reported by adolescents who met the target HbA1c goal (<7%) and their counterparts revealed non-significant difference, suggesting irrelevant impact of this parameter on their perspectives or experiences. Conclusion: The study findings emphasized the need for initiating further intensive awareness programs concerning this disease and its clinical implications in T2DM children to improve treatment adherence, symptoms, and consequently improve the perception of the patient and the family for HRQoL.
Keyword: Adolescents, Type 2 diabetes, Health related quality of life, Saudi Arabia, glycemic control.
DOI: https://doi.org/10.31838/ijpr/2021.13.01.281
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