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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Excipient profile and future possibilities of fucoidan: a review

Author: A.MARY SARAL, MS. F MATHEW
Abstract: Fucoidan is a sulfated polysaccharide which is obtained from brown marine algae mainly. It is an important source of various sugar components. Among them, one of the crucial components is, L-fucose. L-fucose is rarely synthesized in nature but is essential for the metabolic activities of organisms. Fucoidan is attributed to its multifarious biological actions such as anticancer, anti-inflammatory, antioxidant activities, etc. and are rich in phytochemical constituents that are supposed to aid these responses. Fucoidan is widely available in marketed products in the form of dietary supplements. Its application has been extended to the cosmeceutical industry as a skin conditioning agent mainly. Recent fucoidan product that got Generally Recognized As Safe notification from The United States Food and Drug Administration is Maritech® in 2016 which is produced by Marinova and its intended usage is as a food ingredient in conventional foods. So many studies had been already conducted for several of its pharmacological activities except for its excipient nature. The researches proved that fucoidan has an ability to act as an excipient but sufficient studies have not been carried out to explore this potential to the fullest. The excipient nature of fucoidan that is proven is; emulsifying agent, anti-aging, viscosity-enhancing agent, skin-protective agent, etc. Hence the main objective of this write-up is to point-out the excipient potential of fucoidan and help the researchers to develop a pocket and patient-friendly medicine.
Keyword: Fucoidan, Brown algae, Sulfated polysaccharides, Excipients, Dietary supplements.
DOI: https://doi.org/10.31838/ijpr/2020.12.04.517
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