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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Comparison of the Effectiveness of Ciprofloxacin Drops with Levofloxacin Drops in Patients with Chronic Suppurative Otitis Media (CSOM) between 2016-2019

Author: GHOLAM-ALI DASHTI KHAVIDAKI, REZA GHARIBI
Abstract: Introduction: a significant part of health care costs has been allocated to chronic suppurative otitis media as one of the most common causes of hearing loss in the world. This budget has been assigned for treating and reducing the complications of this disease. This study compared the effectiveness of ciprofloxacin drops with levofloxacin drops in patients with chronic suppurative otitis media (CSOM). Materials and Methods: participants including 150 patients with chronic suppurative otitis media in Zahedan took part in this clinical trial study. This sample was randomly divided into two groups receiving ciprofloxacin drops and levofloxacin drops. Data has been collected from information form and analysis was done by SPSS software and t-test. Results: The discharge improvement after the intervention in two groups showed a significant increase in compare to the stage before intervention or treatment. (P= 0.024). Moreover, patients' hearing loss improved increasingly in two groups of levofloxacin and ciprofloxacin before treatment in compare to after intervention. A significant difference was detected between both groups (P =0.038). In addition, there was not a significant difference between both groups regarding pain improvement. Discussion and Conclusion: results showed the significant effect of Levofloxacin drops reducing symptoms of the disease rather than ciprofloxacin drops. Moreover, former drops revealed their supremacy in improving hearing loss and discharge. It should be mentioned that there was not detected any pain improvement by using both drops.
Keyword: Chronic Suppurative Otitis Media, Ciprofloxacin Drop, Levofloxacin Drop
DOI: https://doi.org/10.31838/ijpr/2020.12.04.512
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