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The Influence of Cigarette Smoking in Immunoglobulin-E and Interleukin-33 Levels in Iraqi Smokers
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| Author:
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SHEREEN AL-ALI
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| Abstract:
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Cigarette smoking is one of the serious issues that has been uncommonly addressed in studies in Iraq. Recently, it has been spread widely raising red flags to pay attention to it. The aim of the study is to estimate the level of Total immunoglobulin-E (IgE) and interleukin-33 (IL-33) in smokers living in Basra Iraq and find the correlation between the two parameters to understand the mechanism occur during smoking. Sixty participants (30 smokers and 30 non-smokers) were included in this study. Five ml of blood used to estimate the levels of Total IgE and IL-33 in both groups in serum. The correlation between Total IgE and IL-33 was found using Pearson correlation. The results showed that all of our subjects were male smokers and the majority were at old ages. Moreover, the mean level of Total IgE was significantly higher in smokers (97.81 IU/ml), in compare to non-smokers which was 10.61 IU/ml. Similarly, the mean level of IL-33 was significantly higher in smokers 4.19 ng/L, in compare to non-smokers which was 3.05 ng/L. Additionally the results showed an inverse correlation between Total IgE and IL-33. In conclusion, the present findings showed that cigarette smoking is more prevalence in men than women in Basrah. The elevated levels of Total IgE and IL-33 indicate that symptoms in smokers are related to the asthmatic symptoms. The invers correlation between the two parameters suggest that the role of IL-33 might change during long periods of smoking.
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| Keyword:
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Cigarette smoking, IgE, IL-33, ELISA, Iraq
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.299
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| Download:
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Request For Article
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