|
Flaxseed as A Choice in The Treatment of Non-Alcoholic Steatohepatitis – A Review
|
|
| Author:
|
MAITHRI SHANBHOGUE H, PREETHI S, AMIT B PATIL
|
| Abstract:
|
Purpose: Non-alcoholic steatohepatitis (NASH) is a disease that depends on various causes and its progression is not properly elucidated, hence one treatment may not be effective. It has remained undiagnosed due to the absence of any prominent symptoms and the only way to diagnose NASH is by liver biopsy. At present, the treatments that are available act indirectly by either targeting liver functions or obesity. Many drugs like selonsertib, elafibranor are being explored and are still in clinical trials. In this article, we are focusing on the treatment of NASH through the herbal approach as they have no known adverse effects and contain several components that may be helpful to treat the disease.
Methods: This paper summarizes the methods to separate the chemical components of flaxseed, its application in the treatment of NASH, and the challenges in designing an herbal product.
Results/Outcome: On reviewing few published articles, it was shown to possess health benefits like decreasing blood pressure, preventing the risk of cardiovascular diseases, reducing cholesterol, hepatoprotective, antidiabetic, antisteatotic, and antioxidant activities. After separation of the chemical constituents, they are further used to formulate edible film, microcapsules, and so on.
Conclusion: Some current researches on Herbal medicines have shown the potential to make the currently existing conventional medicine more efficient when these two systems of medicine are merged together. On evaluating the pharmacological activities possessed by herbal components, they can be either used alone or in combination with other classes of drugs like antioxidant, antiobesity, and insulin sensitizers for effective treatment of NASH.
|
| Keyword:
|
NASH, Fatty liver, Herbal medicines, Diabetes, Obesity.
|
| EOI:
|
-
|
| DOI:
|
https://doi.org/10.31838/ijpr/2021.13.01.166
|
| Download:
|
Request For Article
|
|
|