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Personalized medicine: A Review on scope and its pitfall
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| Author:
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, VEERAPPAN MUTHUSAMY, ARAVINDHANATHAN VENKATESAN, ARUN RADHAKRISHNAN, GOWTHAMARAJAN KUPPUSWAMY
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| Abstract:
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Personalized medicine, which is both encouraging and exciting that a new effort is underway to create tailor-made medicine and medical treatments by drawing on exceptionally detailed and extensive biomedical data. Each patient is unique; hence “one size fits all” is not effective which are currently used in HealthCare. Here these are the tailoring of medicine in which dosage forms can be formulated in a challenging basis, based on the Genomic information of the patients which may lead to a success rate of completely curing the disease. Personalized medicine also helps to diagnose patients in a highly specific manner, allowing more effective and targeted therapy. Formulation opportunities are more for these approaches, which already exist in a market particularly 3D Printing of Tablet, mini pills, film dosage forms and also in immunotherapy. Though it having more advantages, it faces more challenges as we are already in a Prescribing medication using “Trial & Error method” which was preferred by long period of time; and numerous issues which have started to arise, including legal (intellectual property rights and Regulatory frameworks), Ethical and Social issues (Confidentiality and Privacy of Patients). Patient privacy, if patient’s genetic data was leaked, many issues may be presented. For example, inappropriate use of this information by insurance companies, who may not offer policies to certain individuals with genetic diseases. As all the industries presently targeting prescribing medicine, because of personalized medicine the excipient grade may have to change because of Technologies involved, such as 3D printing, and it may lead to change in formulation strategy. In other hand, Scientific and Technological advances in the genomics field mean that cost and time are no longer a barrier for precision medicine. Moreover personalized medicine, the effort is ambitious, challenging and possible.
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| Keyword:
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Personalized Medicine, Precision Medicine, Formulations, Legal and social issues.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.141
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| Download:
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