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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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An updated review based on literature -Traditional use, Phyto- chemistry and Pharmacology of Leea indica (Burm.f.) Merr

Author: LINGARKARSILPAVATHI, MUKESH KUMAR DAS, SOVAN PATTNAIK, DEBAJYOTI DAS
Abstract: Since time immemorial, plants proved to have therapeutic potential and were used by human civilizations to treat various ailments. However, the chemotaxonomy based systematic study of plants gained momentum in the recent past. This systematic study entails a detailed exploration of plant species present in a genus and the chemical constituents present in each plant. In this communication, we performed an in-depth review of Leea indica (L.indica) and its isolated components from the research reports obtained from PubMed and Science Direct databases. The conclusion of this scrupulous review suggests that Leea indica (Burm.f.) possesses various essential phytoconstituents and derived compounds. Some of these compounds exhibit potential biological activities like anti-proliferative, antioxidant, antimicrobial, cytotoxic, anti-anxiety, antifungal, hepatoprotective effect. Besides, L.indica proved to be effective against fever, diarrhea, dysentery, skin diseases, gastric ulcer, asthma, bone fracture, headache, and many other conditions. Amongst several derived and isolated chemical moieties, triterpenoids and phenols are the significant components of L.indica. Similarly, MAA, MAX, gallic acid, and quercetin are among the other constituents, which are the best remedy to treat cancer. From this review, it is evident that Leea indica has got potential therapeutic significance that has to be proved pharmacologically.
Keyword: Leea indica, phyto-constituents, pharmacology, biological effect, traditional uses
DOI: https://doi.org/10.31838/ijpr/2021.13.01.135
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