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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Comparison of surgical field bleeding during endoscopic sinus surgery between GTN-Esmolol and Remifentanil as hypotensive anesthesia techniques: Randomized control trial single center institution

Author: ALI NAJEH AL-KHAYYAT, JAAFAR HAMEED JAAFAR MAHBOBA, RAFAL ZUHAIR JABER AL-SHAMMARI
Abstract: Endoscopic sinus surgery bloody field made challenge during surgery, to compare blood loss, surgical satisfaction, suction needed and vital stability during functional endoscopic sinus surgery between two groups. It is randomized, controlled trial on 70 patients in Iraqi people in Al-Sader Medical City in Al-Najaf city, both (ASA) class one or two undergoing functional endoscopic sinus Surgery.35 patient received Remifentanil. Thirty-five patients took Glycerin trinitrate - esmolol, anaesthetized by intravenous Propofol plus Atracurium as induction with, ketamine analgesic dose plus inhalational anesthesia as maintenance. The early results weighted by the Boezaart grading scale to evaluate operative area. Bleeding less severe in patients who took Remifentanil in comparison to those who get Glycerin trinitrate - esmolol, patients who received Glycerin trinitrate - esmolol had a significant decrease in Glycerin trinitrate in comparison to those taking Remifentanil. The times of need of suction, bradycardia more significant in those who received Remifentanil in comparison to another group of patients, recovery time more prolonged with Remifentanil but no significance according to the duration of surgery between two groups. Remifentanil provides better surgical field regarding blood loss and suction times and less effect on pressure of the blood and with spastically significant bradycardia in comparison to using of Glycerin trinitrate -esmolol in Functional Endoscopic Sinus Surgery, also, Remifentanil provide reasonable surgical satisfaction in compassion to Glycerin Trinitrate – esmolol.
Keyword: Functional Endoscopic Sinus Surgery, hypotensive anesthesia, Remifentanil, Glycerin trinitrate-Esmolol
DOI: https://doi.org/10.31838/ijpr/2020.12.03.469
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