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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Morphometric characteristics of parts of rat kidney nephron in normal and under the influence of an antiseptician - facility 2 road stimulator on the background of chronic radiating disease

Author: JUR'AT J.BAKHRONOV, SHUKHRAT J.TESHAEV, MUSHARRAF S.SHODIEVA
Abstract: In the experiment on rats, a comparison was made of the morphological changes in parts of rat kidney nephron normal and under the influence of ASD fraction 2 against the background of chronic radiation sickness. It was found that after exposure to chronic radiation, the parameters of renal tissue nephrons decrease, and the correction of the ASD of fraction 2 accelerates the regeneration of damaged tissues. To establish the dynamics of changes in morphometric parameters of the area of the renal corpuscle, proximal and distal convoluted tubules of the kidneys of 6-month-old rats in normal conditions and under the influence of ASD fraction 2 against the background of chronic radiation sickness. The effect of tissue drug ASD-2 as correctors can be explained by the fact that this drug reduces the production of free oxygen radicals, which have damaging effects on biological membranes of cells, proteins, nuclear chromatin, and also disrupt the stability of ion channels and receptors.
Keyword: nephron, proximal convoluted tubule, distal convoluted tubule, chronic radiation sickness, ASD-f2.
DOI: https://doi.org/10.31838/ijpr/2021.13.01.102
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