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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Estimation Of Salivary Ph, Buffering Capacity And Flow Rate In Early Childhood Caries ( Ecc )

Author: FARHAT SADIQUE, VISHNU PRIYA.V, GAYATHRI.R
Abstract: Saliva is a heterogeneous fluid comprising proteins, glycoproteins, electrolytes and small organic molecules that are constantly in contact with the teeth. There are many biological factors in saliva that protect enamel, dentin and cementum from caries and help in remineralization. This study focuses on the salivary flow rate, pH, buffer capacity and their relationship with early childhood caries (ECC) and the potential of saliva as a potential biomarker in the diagnosis of Early childhood caries. The saliva samples of 20 children between the age group of 5 to 7 years with early childhood caries were collected in sterilized containers. Similarly samples from healthy, caries-free children were also collected in separate containers. The salivary flow rate, pH and the Buffering capacity of the samples were determined. The results obtained were then analysed and compared. The average salivary flow rate is found to be 0.3 mL/min for all the children irrespective of presence of caries. The average salivary pH of the ECC samples is found to be 6.5, The average buffering capacity for the ECC samples is 5.3. From the data collected we found that there is no correlation between caries activity and salivary flow rate. The most significant differences in values was seen in buffering capacities of the samples. This study highlights the further in depth investigations required to determine the exact relationship between the physicochemical properties of saliva like flow rate, pH and buffering capacity.
Keyword: Saliva, Physiochemical properties, salivary flow rate, pH, Buffering capacity, Early childhood caries.
DOI: https://doi.org/10.31838/ijpr/2020.12.03.456
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