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Assessment Of Salivary Ph In Patients With Oral Submucous Fibrosis
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| Author:
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T.N.UMA MAHESWARI, DHANVANTH
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| Abstract:
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Background: Oral submucous fibrosis is a chronic debilitating disease of the oral cavity characterised by inflammation and progressive fibrosis of the submucosal tissues. Oral submucous fibrosis results in marked rigidity and an eventual inability to open the mouth and is considered as most prevalent potentially malignant disorders with increased malignant transformation rate. Saliva is a complex secretion with varied important functions and also serves as an noninvasive diagnostic tool. Salivary pH estimation is done as one of the biochemical diagnostic markers in many oral and systemic diseases , hence its role in diagnosis of early malignant changes in oral submucous fibrosis needs to be explored.. The aim of the study is to assess the variations in salivary pH in patients with various grades of Oral submucous Fibrosis.
Materials and methods: Saliva samples were collected from 60 patients among which 30 were patients with OSMF. Salivary pH analysis was done with the help of a pH measuring instrument named “HI5221-advanced research grade benchtop pH/mV meter” which is also waterproof Laboratory pH meter.
Results: Out of 60 outpatients 30 patients were in the control group and 30 patients were in the OSMF group, Males 64% were higher compared to females 36% in the control group and 18 males and 12 females in OSMF groups. The OSMF patients with age group of 30 - 40 years were in higher prevalence.The salivary pH shows a mean value of 7.2 pH in the control group and 5.9 pH in the OSMF group. The salivary pH 6.1 has higher prevalence in OSMF patients 16.6%. The highest prevalence of OSMF grading seen in grade 1 56.6%. The highest prevalence of type of tobacco used by OSMF patients seen in areca nuts 43.3%. On comparing association between type of tobacco and OSMF grading, 16% of Areca nut and betel quid are the most common tobacco used and more predominant in Grade 1 OSMF patients. On comparing association of salivary pH of OSMF patients and OSMF grading the Grade 4A and 4B OSMF patients have salivary pH 5.2.5.3 respectively which is acidic pH. On comparing association between salivary pH and tobacco used in OSMF patients the salivary pH 5.20 which is acidic is higher in areca nut using OSMF patients.
Conclusion: OSMF patients have hyposalivation and slightly acidic salivary pH level compared with normal individuals. The mean pH of OSMF patients is 6.1. The reduced salivary pH could be a significant initial symptomatic sign of OSMF and helpful in early diagnosis and management with the help of pharmacotherapy, physiotherapy, and a proper, balanced diet. Collecting saliva as a diagnostic tool can be considered as a standard diagnostic indicator being an non invasive procedure and economical. In future many studies have to be experimented on salivary changes among OSMF patients and alterations in these levels that affects the overall quality of life of OSMF patient with increased risk for malignant transformation.
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| Keyword:
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Oral submucous fibrosis; Saliva; Salivary pH, Grades of OSMF, chewing tobacco
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.04.425
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| Download:
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