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Antioxidant and Antihypercholesterolemic Potential of Methanolic Root Extract of Salacia Oblonga- An In Vitro Study
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| Author:
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V.A.MURALIDHARAN , R.GAYATHRI, V.VISHNU PRIYA
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| Abstract:
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Salacia oblonga , an inhabitant of tropical regions of India & Sri Lanka has been used in the traditional Ayurveda system. It is a climbing shrub with densely warty branches. Leaves are oblong, green, veined, and borne on stalks up to 1 cm long.It is a part of folk medicine and the extracts are used to treat diabetes.This study is conducted to assess the antioxidant and Antihypercholesterolemic potential of methanolic root extract of Salacia oblonga.The methanolic root extract was prepared, concentrated and stored.In vitro antioxidant activity was measured by DPPH assay and NO radical scavenging assay. Antihypercholesterolemic potential was also analysed.The methanolic root extract of Salacia oblonga was proved to possess a good level of antioxidant (82% inhibition at 500 µg/ml) and anticholesterol activity(75% inhibition at 500 µg/ml) in this study. The data obtained from the study depicts that the root extract possesses both antioxidant and anti cholesterol activity. Thus the extract can scavenge the free radical accumulation and prevent early onset of cardiovascular related disorders and also lifestyle oriented disorders like diabetes, hypertension etc.
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| Keyword:
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Cholesterol; antioxidant; Salacia oblonga; root extract; free radical scavenger
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.364
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| Download:
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