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Evaluation of mean platelet volume before and after iron deficiency anemia treatment.
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| Author:
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SAFA A.FARAJ, ALAA M. AL-RUBAE, AHMED I. ANSAF
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| Abstract:
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Iron deficiency anemia (IDA) is the most common nutritional anemia and a significant public health problem in the world. Iron reduces megakaryopoiesis so that anemia with iron deficiency (IDA) contributes to micro thrombosis. Iron treatment improve thrombocytosis.
Aims: the purpose is to assess the importance of mean platelet volume (MPV) in the diagnosis of iron deficiency anemia (IDA) in low-setting regions.
Patients and methods: From the period January 1st, 2016 to December 31st, 2018, in the pediatric unit of the AL-Karama teaching hospital, a retrospective study was carried out. A total of 51 patients diagnosed with iron deficiency anemia (35 were males, and 16 were female). The mean patients’ age was 4.9 years, ranging from 9 months to 14 years. Patients with other types of anemia were excluded.
Result: In the pretreatment phase, the mean Hb was 8.1 g/dl, mean MCV was 60.7FL, and the MPV was 5.8FL. In the post-treatment phase, the mean Hb was 10.7g/dl, mean MCV was 68.2 FL, and the MPV was 6.7 FL, p-value (0.0001) was significantly higher in post-treatment group than those in pretreatment group and all patients respond to treatment. From the ROC curve analysis of MPV in patients in pretreatment and post-treatment period, the sensitivity was 76% and specificity 47% at a cut-off level of 5.8.
Conclusion: MPV can be considered as marker that help in diagnosing iron deficiency anemia and for follow up.
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| Keyword:
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Iron deficiency, platelet volume, blood parameter.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.081
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| Download:
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