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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Cytokines: The Immune Warriors in Periodontal Health and Disease- An Overview

Author: DR.JAIDEEP MAHENDRA, DR. SHRUTHI CHANDRASEKARAN, DR.LITTLE MAHENDRA
Abstract: Periodontitis is a chronic inflammatory disease of multifactorial origin. The microbial, genetic, environmental and host immune components play a pivotal role in the nature of disease progression. The fundamental mechanism governing the nature of host tissue destruction highlights the role of inflammation and its various mediators. Amongst the various inflammatory mediators, cytokines play an important role in the maintenance of tissue homeostasis and host inflammatory response against periodontal pathogens. Cytokines are molecules produced by almost all cells of the body and play a significant role in defence and destructive mechanisms of the body. It is important to understand the nature of cytokine biology, its various forms and its responses, in order to manipulate its effects on the periodontal tissues through immune modulating drugs. Hence, this review paper highlights the important aspects of cytokine biology and its evolution, the various pro and anti-inflammatory mediators and its role in periodontal pathogenesis.
Keyword: cytokines, periodontitis, biomolecules, immune response, growth factors
DOI: https://doi.org/10.31838/ijpr/2021.13.01.009
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0.12
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