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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A Prospective Study On Effect Of Vitamin-D Treatment In Diabetic Patients With Chronic Foot Ulcer

Author: RANGABASHYAM S.R, KOTHAI RAMALINGAM, NANDHINI K., POOVARASAN M., PRAVEEN KUMAR V., ARUL BALASUBRAMANIAN
Abstract: The present study was aimed to evaluate the efficacy of Vitamin D in the adjuvant treatment of diabetic foot ulcers to find out its efficacy on wound healing in chronic cases. This prospective observational-based study was conducted in a tertiary care hospital at Salem district, Tamil Nadu. A sample size of 100 patients supports the proposition that vitamin D deficiency impairs the wound healing of diabetic foot ulcers. 50 chronic foot ulcer patients who have been treated with Vitamin D with a standard dose of 2000 IU/day for six weeks and another 50 patients who have not treated with Vitamin D from the department of general medicine were selected for the study. The length, width, and depth of the ulcer were noted before and after the treatment. The significant increase in serum vitamin D levels has produced a significant reduction in ulcer size. The mean reduction of ulcer length and width of the patients treated with Vitamin D was found to be 0.4±0.1 cm, whereas the untreated patients' reduction was only 0.1±0.1 cm. This study proves the efficacy of vitamin D in improved healing of chronic diabetic foot ulcers. Thus, vitamin D supplements can be considered as a treatment strategy for infection control and faster healing of chronic diabetic foot ulcer as it boosts the immune system.
Keyword: Vitamin-D Treatment
DOI: https://doi.org/10.31838/ijpr/2020.12.03.428
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