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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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The Incidence of Postoperative Sore Throat after Local Application of Different Lidocaine Forms & Methods; a Narrative Review

Author: MAJID ALHAMAIDAH, HUSSEIN ALKHFAJI, HUSSEIN ALI HUSSEIN, SAMI RAHEEM HASAN, MOHAMMED ABDUL ZAHRA SASAA, ALI ZAIDAN ALOMARAN, AMJED QASIM MOHAMMED, ALI B. ROOMI
Abstract: Background: sore throat is a well-known complication of endotracheal tube after general anesthesia. Many pharmacological methods to reduce the incidence of sore throat with different lidocaine routes and formulas have used clinically by anesthesia providers. The aim of this review was to explain narratively the efficacy of various ways of lidocaine application in decreasing postoperative sore throat. Methods: All relevant and published data were independently searched by using MEDLINE and EMBASE bibliographic databases, the Cochrane Central Register of Controlled Trials (CENTRAL) and manually using the proper search terms in either the title or abstract. Results: we included 10 studies in this narrative review, involving 1266 participants. 543 of those patients received topical lidocaine therapy, and 723 were introduced as comparative or control groups. 23% (n=226) of lidocaine groups in 3 studies with different forms showed decreased risk of postoperative sore throat, 4 studies ( 39% n= 201) showed no longer significance and 3 studies (38% n= 207 ) showed increased the risk of postoperative sore throat. Authors' conclusions: in our narrative review, most of included studies showed that local anesthetic lidocaine can reduce the incidence of sore throat if used to inflate the endotracheal tube cuff or in combination with other pharmacological or technical ways such diclofenac sodium gel and thermally soften endotracheal tube.
Keyword: sore throat, lidocaine, lignocaine, postoperative, tracheal, endotracheal tube, Complications and general anesthesia.
DOI: https://doi.org/10.31838/ijpr/2020.12.02.356
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