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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Fluid Therapy for Major Abdominal Surgery: A Narrative Review

Author: HUSSEIN ALI HUSSEIN, MAJID FAKHIR ALHAMAIDAH, HUSSEIN ALKHAFAJI, SAMI RAHEEM HASAN, ALI B. ROOMI
Abstract: Fluid therapy is a crucial key in anesthetic management during general surgery because most of assessment studies and trials had a conclusion of the important role of fluid administration and replacement during surgery to improve patient outcomes. In many protocols, fluid therapy in the perioperative period of major surgery is managed by the anesthesiologist. To create an effective plan for the liberalization of fluids during major surgery require good conservation and knowledge of fluid physiology in the human body as well as knowledge of the basic characteristics of all available intravenous fluids, understanding type of surgery and related effects. The general objective of our review is to find the outline of essential basics for fluid therapy during prolonged surgical procedures. Avoidance of fluid and electrolyte imbalance, sufficient tissue perfusion and continuous normality of homeostasis are the most important targets of fluid infusion for anesthetized patients. Colloid or crystalloid? Is still an argument in this field due to the paucity in results from studies to pinpoint the appropriate volume and type of fluid? For this reason, encouragement for more clinical trials is existed and also to appear by a substantial definition for restrictive and liberal fluid therapy. In the last decades, balanced crystalloids are more preferred to compensate for the fluid loss according to most depending trails, but in a restricted plan during surgery.
Keyword: Major surgeries, fluid replacement, liberal method, restrictive method and IV fluid.
DOI: https://doi.org/10.31838/ijpr/2020.12.02.352
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