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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Comparing the Levels of Some Trace Elements with Liver Enzymes in Chronic Renal Failure Patients with Viral Hepatitis B and or C

Author: ALAA HUSSAIN HASSAN, SUHAIR SHATTI SALIH, ALIA KATHEM SALIM
Abstract: The object of this work was to assess the association amongst copper, zinc and iron in contrast with liver enzymes (ALT, AST and ALP) level in chronic renal failure patients with hepatitis B or C. Serum samples were obtained from 90 patients with chronic renal failure (CRF) submission to hemodialysis (HD) at the hemodialysis unit in AL kindy hospital, Baghdad, Iraq in 2019. The ninety patients who enrolled in this study were; 30 patients with hepatitis B virus, 30 patients with hepatitis C infection and 30 patients devoid of hepatitis virus. The concentration of zinc, copper and iron were resolute by means of atomic absorption spectrophotometer (AAS), liver enzymes determined with an autoanalyzer system. A significant correlation was found between means of Cu in CRF patients with hepatitis C and AST in CRF patients without hepatitis with p_ value < 0.05 and Cu with AST in CRF with hepatitis B. Also a significant correlation was found between means of Zn and AST in both groups of hepatitis patients with chronic renal failure, between Zn and ALP in chronic renal failure patients without hepatitis, p_ value < 0.05, According to Zn means there was a highly significant correlation in CRF patients without hepatitis with those who had hepatitis C virus p_ value 0.003.
Keyword: Zinc; Copper; Iron; Viral Hepatitis; Liver Enzymes
DOI: https://doi.org/10.31838/ijpr/2020.12.01.330
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