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Molecular Typing and Antimicrobial Susceptibility Patterns of Escherichia coli Isolated from patients with urinary tract infection.
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| Author:
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AHMED REMTHAN HUSSAIN, MANAL BADI SALEH
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| Abstract:
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Escherichia coli (E. coli) represented most widespread microbes in the world, capable to cause varies disease such as intestinal or extraintestinal disease and also to be opportunistic infection. This study was conducted to isolate E. coli from urine of patients with urinary tract infections at Al- habbobi Teaching Hospital, during the period from November 2018 to March 2019, to detect Phylogenetice groups for isolates and susceptibility to antibiotic. A total of 127 samples patients were collected from urine gave 40 (31%) E. coli. Phylogenetic analysis basedw on the presence or absence of chuA, yjaA and TspE4.C2 marker genes, was carried out to 40 isolates of UPEC, showed that Phylogenetic group B2 was most, predominant, which included 30(75%) isolates, group A 5(12.5%) isolates and group D 5(12.5%) isolates. Antibiotic resistance exhibited group B2 was resistance 97% to Augmentin, 97% trimethoprim, 87% tetracycline and ceftriaxon 80%. Group A and D 100% resistance for each of the Augmentin, trimethoprim and tetracycline. Group A resistance 20% to ceftriaxone and group D was 100%. In This study the phylogentic group of E. coli B2 the majority predominated in UPEC and large resistance to antimicrobial.
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| Keyword:
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Phylogenetic typing groups, Uropathogenic E. coli , Antibiotic resistance
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.328
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| Download:
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