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Association of EBV with Hodgkin and Non-Hodgkin Lymphoma for Females and Males Patients: Histological, Molecular and Survey Study in Karbala, Iraq
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| Author:
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, , ABEER CHEAID YOUSIF AL-FATLAWI
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| Abstract:
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Infection with Epstein-Barr virus (EBV) is closely related to different malignant lymphoma subtypes, such as non-Hodgkin lymphoma (NHL) and Hodgkin lymphoma (HL). NHL and HL are among the world's most popular hematological malignancies. Originating from lymph tissue, with varied biological and clinical features. We aimed at determining EBV prevalence in NHL and HL. Present study classified in to two parts. Part I: survey study for (3 years) include 359 specimens (186 female and 173 males). In females found the percentage of NHL (35.1%) as compared to HL (64.9%). While in male, found HL (57.2%) as compared to NHL (42.8%). High significant differences (P=0.0001) between HL and NHL in the age group (5-14). In females, high significant differences (P=0.0001) between HL and NHL in the age group (25-34). The highest distribution of sites of lymphoma found in cervical lymph node for both gender. Part II: laboratory study includes 40 specimens divided in to four groups according to the gender and subtype of lymphoma. High significant differences in the age (P=0.008) between HL and NHL of males, significant differences (P= 0.038) in the presence of EBV. High significant differences in the age (P=0.001) between HL and NHL in females. In addition, significant differences in presence of EBV for both HL and NHL of males. While significant differences (P=0.06) in presence of EBV found only in NHL of females.
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| Keyword:
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Histology, Non-Hodgkin lymphoma “NHL”, Hodgkin lymphoma “HL”
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.327
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| Download:
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