|
Aspirin Effect on Mid Luteal Phase Doppler Indices in Patients with Recurrent Pregnancy Loss
|
|
| Author:
|
WASSAN NORI, FATIN SHALLAL, MUNA ABDUL GHANI.ZGHAIR
|
| Abstract:
|
Objective: to assess the effect of Aspirin on Doppler indices in a patient with recurrent pregnancy loss.
Materials and Methods: a prospective interventional study, conducted in Al-Yarmouk teaching hospital in the department of obstetrics & gynecology Baghdad - Iraq from the 1st of January 2019 to the 1st of January 2020. Recruited a hundred women, fifty of them had a history of recurrent pregnancy loss ( study group) along with fifty fertile women who at least had one live child ( control group), all women were subjected to trans vaginal Doppler study at the mid-luteal phase; Pulsatility index PI, Resistance index RI and endometrial thickness were recorded for comparison along with demographic criteria. The study group received aspirin 75 mg for 3 months after which another Doppler study was made & new readings recorded for comparison.
Result: The study group showed a significant increase in PI compared to the control (p-value 0.044).A higher endometrial thickness ET (p-value0.002) & progesterone level( p-value 0.002)were observed in the control group, after adding aspirin 75mg for 3 months the Mean PI and RI significantly reduced in the study group (20%, and 18.2% reduction for PI and RI), while ET increased by 8.5%.
Conclusion: the observed changes in doppler parameters indicate improvement in the blood flow to the endometrium, an effect that may be of value in managing RPL patients improve their fertility potential
|
| Keyword:
|
Recurrent Pregnancy Loss, uterine artery Doppler, pulsitability index, resistance index,mid-luteal phase, Aspirin.
|
| EOI:
|
-
|
| DOI:
|
https://doi.org/10.31838/ijpr/2020.12.03.413
|
| Download:
|
Request For Article
|
|
|