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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Clinicopathological Profile of Cervical Lymphadenopathy: An Observational Study;

Author: , NEHA SURESH KUMAR SHARMA, SUJATA R. KANETKAR, DR. A.Y.KSHIRSAGAR, ANAND GUDUR, VAIDEHI NAGAR, SUPRIYA KARMAKAR;
Abstract: Background Cervical lymphadenopathy (CL) is one of the most common and worrisome presentations of the underlying pathology in the head and neck region with many differential diagnoses with similar presentations. The pathologies associated with CL range from inflammation and infection to malignancy. Thus, comprehensive clinicopathological knowledge of CL would allow for timely diagnosis and reduction in morbidity and mortality. Objective To evaluate the clinicopathological profile of patients who presented with CL. Materials and Methods This hospital-based prospective study was conducted on 167 patients who presented with CL at a tertiary care hospital in Karad, Maharashtra, from June 2017 to May 2019. A detailed clinical history was documented, followed by a thorough local examination and routine blood investigations for all the patients. Results The most common lesions seen were tuberculous lymphadenitis (41.26%), metastatic lesions (27.78%), and reactive lymphadenitis (24.60%). Reactive lymphadenitis (38.2%) and tuberculosis (25.8%) were found to be common in 21-30 years of age, whereas metastasis was common in the age group of 61-70 years (36.17%). The posterior triangle group of lymph nodes was the most affected in tuberculosis in 30.65% cases and in metastasis upper jugular lymph nodes was most commonly affected in 36.17% cases. Neck swelling (100%) and fever were the most common presenting symptoms (53.89%) followed by cough (35.93%). Of the 60 patients with anemia, 34 patients had metastasis in the lymph nodes (56.67%) and 16 had tuberculous lymphadenitis (26.67%). Conclusion CL is the presenting sign in a heterogeneous group of diseases with variations according to age, geographical distribution, anatomical location of the CL, and the signs and symptoms; a thorough knowledge of which allows for rapid diagnosis and treatment planning.
Keyword: Lymphadenopathy, Lymph node, Neck, Tuberculosis lymph node
DOI: https://doi.org/10.31838/ijpr/2020.12.03.391
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