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Hospital-acquired urinary tract infections in indoor patients with indwelling foley’s catheter: A prospective study in a tertiary care teaching hospital
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| Author:
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PIYUSH PRAJAPATI, SWATI AUNDHAKAR, V.C PATIL
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| Abstract:
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Globally, research indicates that urinary tract infections (UTIs) are commonly associated with the usage of indwelling urinary catheters. Higher prevalence of catheter-associated UTIs (CAUTIs) in hospitalized patients and conflicting results in established literature pertaining to the determinants of CAUTIs inspired us to evaluate CAUTIs and their antibiotic susceptibility pattern. In this prospective study, a total of 196 patients of either gender, aged =18 y with initial microbial-free urine culture, who were catheterized for more than 48 h were included. Microbial surveillance was conducted by quantitative culture method followed by antibiotic susceptibility tests. R version 3.6.0 software was used to analyze the data. Out of 196, majority were males (60.2%) and the mean age was 55.3 ± 16.5 years. Of the 30 (15.30%) patients who had CAUTI, 24 were females and 6 were males. Majority (9; 30%) of the CAUTI patients were in the age group of 51-60 y. Females were 8.3 (95% CI: 3.2-21.5) times more likely to have CAUTI compared to males. Significant association was found between CAUTI and medical conditions such as diabetes (P=0.011) and renal failure (P<0.0001). A higher incidence of CAUTI was noted in the second week (54.23%) followed by first week (33.71%). With one-day increase in the duration of catheterization, the odds of increase in the incidence of CAUTI was 1.40 (CI: 1.2-1.7; <0.001). Escherichia coli (37.1%) and Klebsiella (25.71%) were the most commonly encountered uropathogens of CAUTIs. Uropathogens were most susceptible to Tigecycline (96.7%), Colistine (70%), Amikacin (40%), Nitrofurantoin (40%), Cotrimoxazole (30%), and Carbapenem (26.7%). Prolonged catheterization and hospital stay, comorbidities (diabetes and renal insufficiency), and advanced age were found to be significant risk factors for CAUTIs. Escherichia coli were isolated the most in the cultures.
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| Keyword:
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Urinary catheters; Infections; Escherichia coli
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.03.386
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| Download:
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