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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Assessment of ns1, igg and igm antibodies in suspected dengue patients

Author: SHARMILA R, N.P.MURALIDHARAN
Abstract: The diagnosis of dengue and the differentiation between primary and secondary infections is crucial for monitoring the unfolding of the epidemic and figuring out the hazard of severe sorts of the disorder. The detection of immunoglobulin IgM and IgG antibodies is the principal method for the laboratory diagnosis and prognosis of dengue. The present study also assessed the application of a rapid test for dengue regarding the detection of new instances, reinfection reputation, and estimation of the epidemic attack rate. This is a retrospective study done during the dengue outbreak in Chennai between August and November. The 100 patients samples were collected who were reported positive with a rapid diagnostic test. In the rapid test 100 patients, samples were collected who were positive for the card test. After doing the ELISA test only 17 people had NS1 positive. Among those 17 patients, 12 patients had IgG positive which indicates that the person had infection previously. Therefore only 5 people need hospital care. Diagnostic criteria should be available to the general practitioners in the community to determine NS1, IgG, and IgM values in confirming the clinical diagnosis of dengue infection whether its primary infection or reinfection or dengue primary shock syndrome.
Keyword: Dengue, Antibodies, Reinfection, Primary shock syndrome
DOI: https://doi.org/10.31838/ijpr/2020.12.04.290
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