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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Evaluating The Efficacy Of Abgel Soaked In Manuka Honey Following Extraction Of Infected Mandibular Molars

Author: SNEHA KRISHNAN, SENTHILNATHAN PERIASAMY, MURUGAIYAN ARUN
Abstract: The aim of the present clinical trial study is to assess the efficacy of Abgel soaked in Manuka Honey in reducing postoperative pain, discomfort and soft tissue inflammation following extraction of infected mandibular molars. This prospective study included 40 patients who had been referred to the Oral Surgery Clinic at Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Chennai for extraction in relation to infected mandibular molars under local anesthesia. Randomization was carried out by flipping a coin. The patients were randomly assigned to 2 groups: Group 1, Treatment group(Manuka honey soaked in Abgel applied prior to suturing), Group 2: Control Group( Suturing without application of Manuka Honey). The post surgical pain intensity levels for each patient were recorded and evaluated at 3 days and 7 days after the initial treatment using Visual Analogue Scale(VAS)pain assessment tool. The total analgesic dose following treatment was also evaluated.The post extraction discomfort as well as the clinical signs and symptoms related to soft tissue healing around the extraction socket for each patient were recorded 7 days after the treatment. In this study we observed, VAS scores of the control group at the 3rd post surgical day were significantly higher than the treatment group(Manuka group).(P<0.05) Total analgesic intake in the control group was also significantly higher than the Manuka Group.(P=0.02) However, there was no significant difference in groups in VAS scores on the 7th day (P=0.09) The soft tissue healing index scores were significantly higher in the Manuka Group on the 7th day post surgically as compared to the Control Group. (P<0.05) There was also a significant difference in groups in PoSSE Scores (P=0.05) suggesting an improvement in discomfort in the Manuka Group. Within the limitations of the present study, Abgel soaked in Manuka Honey has been a successful combination in relieving post surgical pain, discomfort and soft tissue inflammation following extraction of infected mandibular molars under local anesthesia.
Keyword: third molar; manuka honey; infection, mandibular molar; postsurgical pain; swelling
DOI: https://doi.org/10.31838/ijpr/2020.12.01.286
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