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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Correlation of VitaminD level with AMH and HMGB1 in pre and post-menopausal women in Babylon province

Author: SHAIMA R.IBRAHEEM, THANAA ABDULMAHDI MOKIF, RAHEEM TUAMA OBAYES AL- MAMMORI, HUSSEIN O.M. AL-DAHMOSHI, NOOR S.K. AL-KHAFAJI
Abstract: From a group of pre and post-menopausal women, respectively (34 and 46) were selected as test samples as well as 24 healthy women as control samples. All the test and control samples evaluated to measure the Total Vitamin level, Anti Mullerian hormone, and HMGB1 level. The study was planned to assess the relationship between Vit. D. level, AMH, and HMGB1 at the Babylon women at age < 45 years as (Pre – Menopausal) and > 45 years as Post-menopausal. The time between sample collection and measure of the studied parameters was in between (Jullay 2019 – Until January 2020) in Merjan medical city, GIT, and Live Center laboratory. Pre-menopausal women show a low level of AMH in comparison with postmenopausal and control samples. postmenopausal women show a low level of HMGB1 in comparison with the premenopausal and the control samples, While the result of premenopausal show that increased level of HMGB1 in comparison with the control sample. Highly significant decrease of VitaminD level of pre- and post-menopausal women in comparison with healthy women. While no significant result of AMH level and significant increase of HMGB1 level. A significant negative correlation of Total vitaminD level with HMGB1 level at both pre and post-menopausal women, on the other hand, insignificant correlation has been found between Vit. D and other parameters.
Keyword: vitamin, HMGB1, AMH, postmenopausal
DOI: https://doi.org/10.31838/ijpr/2020.12.04.238
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