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Application of Purple Leaf Extract (Graptophyllum Pictum) In Wound Healing Process of Collagen Density
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| Author:
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MUHAMMAD BRAHMANTYO, INTAN NIRWANA, DAN DEVI RIANTI
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| Abstract:
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Background: Purple leaves are derived from the Graptophyllum pictum plant, the Acanthacea family contains: flavonoids, saponins, and tannins. Purple leaf extract has anti-inflammatory and analgesic effects.
Purpose: This study observed an increase in the density of collagen in wounds in wistar rats.
Methods: The research subjects were 24 adult and healthy Wistar (Rattus norvegicus) mice, aged 3 months, with a body weight of 200 grams, which were divided into 6 groups of 4 rats each. The making of purple leaf extract is as follows, purple leaf powder weighed as much as 500 grams, then moistened with 96% ethanol as much as 500 ml. Research data were analyzed using the Kruskall Wallis and Mann Whitney tests.
Results: Statistical data analysis using the Kruskall Wallis test showed significant differences in collagen density (P<0.005).
Conclusion: Giving a 15% purple leaf extract gel increases collagen density.
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| Keyword:
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Purple leaf (Graptophyllum pictum), wound healing, incision, collagen.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.04.218
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| Download:
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