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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Comparative Analysis of Bioactive Compounds for Euphorbia hirta L. leaves Extract in Aqueous, Ethanol, and Methanol Solvents using GC-MS

Author: SHIKHA DIXIT, SUGANDHA TIWARI
Abstract: Objective: Euphorbia hirta L. is a traditional folk remedy which is used as anti-inflammatory, anti-allergic, antidiarrheal, antiasthmatic, antidiabetic, antioxidant, anti-tumor activity. In this study, the comparative chemical profiling of Euphorbia hirta L. leaves has been performed in ethanol, methanol, and aqueous extract using GC-MS analysis. Materials and Methods: 10-10 grams of powdered leaves were extracted separately in ethanol, methanol and aqueous solvents for the analysis. Results: The experimental outcomes of GC-MS study of E. hirta L. leaves witnessed the existence of 6 bioactive compounds in aqueous extract, 24 in ethanol extract, and 36 in methanol extract. The molecular structure, formula, and weight of the compounds are determined with the help of National Institute Standard and Technology (NIST) database. Conclusion: The experimental outcomes demonstrate that the methanolic extract of E.hirta L. leaves contains highest bioactive compounds among ethanol, methanol and aqueous extract. Extraction and identification of these bio-active compounds is extremely important for validating the medicinal potential of the herb.
Keyword: Bioactive compounds, biological activity, Euphorbiaceae, Euphorbia hirta L., GC-MS
DOI: https://doi.org/10.31838/ijpr/2020.12.04.145
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