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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Study the perceptions, effectiveness and adherence Pattern of anti-diabetic drugs prescribed for type 2 DM patients in some Iraqi hospitals, specialized diabetic centers and private pharmacies. 20160737/5609

Author: ZAHRAA ALBASRY, LUBAB TAREK NAFEA
Abstract: Background: Type 2 diabetes mellitus incidence has been growing firmly all over the world. It is affecting almost all populations in both developed and developing countries with high rates of diabetes-related morbidity and mortality. Compared with individuals without diabetes, patients with type 2 diabetes mellitus have a considerably higher risk of Long-term complications that affect retina, kidney and nervous system are termed as microvascular complications. The macrovascular complications which include coronary artery disease, cerebrovascular disease and peripheral vascular disease also occur with higher frequency in diabetes. There is no single medication can be used to treat all cases of type 2 diabetes mellitus efficiently, however, the World Health Organization has recently published a list contains the most effective and safe medications used in the treatment and management of type 2 diabetes mellitus. Methods: By a retrospective study, 100 Iraqi diabetic patients (type 2) from different Iraqi hospitals and health care centers were studied regarding to their age groups, gender; the types of treatments used for diabetic mellitus and also for the possibility of drug – drug interaction among medication used by those patients. The data were analyzed using the Chi-Square test, and the univariate and multivariate logistic regression models. Results: The present study shown that the highest rate of incidence for type 2 diabetes mellitus was between the patients of middle age group (41-60 years), they represent 59% of diabetic patients included in this study. Furthermore, among total of 307 drugs prescribed to 100 diabetic patients, 70 drugs were prescribed by their brand names. Average number of drugs per prescription was 3%. This study also showed that the percentage of patients on anti-diabetic mono, dual, triple and quadruple therapy were 48%, 44%, 7% and 1% respectively. Conclusion: This study shows an expanding to the use of trend of anti-diabetic monotherapy, with Biguanides and Incretins which show the more negative and positive trend, respectively.
Keyword: Diabetes mellitus, oral anti-diabetic drugs, World health organization.
DOI: https://doi.org/10.31838/ijpr/2020.12.04.188
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0.12
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