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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Extraction and Optimization of Phenolic Compounds from Sesbania Grandiflora Flower Using Response Surface Methodology

Author: K.K. MOHANA, M.S. SHIVASAMY, J. JONY BLESSING MANOJ, S. SHANGAVI
Abstract: Sesbania grandiflora L. (Agathi) is a well-known small, loosely branching Tropical Asian plant and the consumption of these floral vegetables can cure illness and diseases. Shade dried flowers has higher polyphenol content compared to all other pretreatments like hot air drying, blanching. The influence of microwave assisted extraction for extraction of Phenolic compounds from Sesbania grandiflora flower has not been accounted for yet. Thus the aim of this research is to optimize the extraction using RSM to assess the different combination of microwave power, solid to solvent ratio and time on total polyphenolic content, antioxidant activity and flavanoid content of microwave assisted Sesbania grandiflora flower extract.The optimized value for polyphenol extraction were power-504.10 watt, time-65.85 sec and solvent-14.77ml. The usuage of CCD model gives the best experimental conditions for the selection of extraction. Inorder to optimize the total polyphenol, flavanoids and antioxidant activity of sesbania grandiflora flower extract, Quadratic polynomial model could be used with high correlation.
Keyword: Polyphenols, Microwave assisted Extraction, Sesbania Grandiflora.
DOI: https://doi.org/10.31838/ijpr/2020.12.04.150
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